For 17 years the two states struggled for supremacy, primarily in Italy and Iberia , but also on the islands of Sicily and Sardinia and, towards the end of the war, in North Africa. After immense materiel and human losses on both sides, the Carthaginians were once again defeated. Macedonia , Syracuse and several Numidian kingdoms were drawn into the fighting, and Iberian and Gallic forces fought on both sides. There were three main military theatres during the war: Italy, where Hannibal defeated the Roman legions repeatedly, with occasional subsidiary campaigns in Sicily, Sardinia and Greece; Iberia, where Hasdrubal , a younger brother of Hannibal, defended the Carthaginian colonial cities with mixed success before moving into Italy; and Africa, where Rome finally won the war.
After the war Carthage expanded its holdings in Iberia where in BC a Carthaginian army under Hannibal besieged, captured and sacked the pro-Roman city of Saguntum. Later that year, Hannibal surprised the Romans by marching his army overland from Iberia, through Gaul and over the Alps to Cisalpine Gaul modern northern Italy.
Reinforced by Gallic allies he obtained crushing victories over the Romans at the battles of Trebia and Lake Trasimene Moving to southern Italy in Hannibal defeated the Romans again at the battle of Cannae , where he annihilated the largest army the Romans had ever assembled.
After the death or capture of more than , Roman troops in less than three years, many of Rome's Italian allies , notably Capua , defected to Carthage, giving Hannibal control over much of southern Italy. As Syracuse and Macedonia joined the Carthaginian side after Cannae, the conflict spread. The Romans took drastic steps to raise new legions: enrolling slaves, criminals and those who did not meet the usual property qualification; this vastly increased the number of men they had under arms.
For the next decade the war in southern Italy continued, with Roman armies slowly recapturing most of the Italian cities that had joined Carthage. The Romans established a lodgement in north-east Iberia in BC; the Carthaginians repeatedly attempted and failed to reduce it. In the Romans took the offensive in Iberia and were badly defeated but maintained their hold on the north-east. This new Carthaginian invasion was defeated at the Battle of the Metaurus.
