Official websites use. Share sensitive information only on official, secure websites. Both personalized medicine and nanomedicine are new to medical practice. Nanomedicine is an application of the advances of nanotechnology in medicine and is being integrated into diagnostic and therapeutic tools to manage an array of medical conditions.
Novel nanomedicines have been employed in the treatment of several diseases, which can be adapted to each patient-specific case according to their genetic profiles. In this review, we discuss both areas and the intersection between the two emerging scientific domains. The review focuses on the current situation in personalized medicine, the advantages that can be offered by nanomedicine to personalized medicine, and the application of nanoconstructs in the diagnosis of genetic variability that can identify the right drug for the right patient.
Finally, we touch upon the challenges in both fields towards the translation of nano-personalized medicine. Keywords: nanomedicine, personalized medicine, pharmacogenetics, pharmacokinetics.
Personalized medicine may be defined as the tailored individualized management approach to achieve the right drug at the right dose to the right patient [ 1 ]. Personalized medicine involves proteomic, genomics, and epigenetic studies, as well as specific patient health conditions and environmental influence [ 2 ].
In turn, nanotechnology is a broad term that encompasses systems in the range of 10β nm [ 3 ]. The term also implies the ability to control structures at this nano-range towards a desirable outcome. Molecules at the nano size range could interact with cells at the subcellular and molecular levels as the size allows for this otherwise unattainable interaction at a larger scale e.
