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Official websites use. Share sensitive information only on official, secure websites. Heterosexual transmission is the main driver of the HIV epidemic in Tanzania. Only one estimate of the incidence rate of intra-marital HIV seroconversion in Tanzania has been reported and was derived from data collected between and Moreover, little is known about the specific risk factors for intra-marital seroconversion in Tanzania. Improved evidence around factors that increase the risk of HIV transmission to a serodiscordant spouse is needed to develop and improve evidence-based interventions.
We sought to investigate the rate of intra-marital HIV seroconversion among HIV sero-discordant couples in Tanzania as well as its associated risk factors. The rate of seroconversion was analyzed by survival analysis using non-parametric regressions with exponential distribution. We found serodiscordant couples, 14 of which had a seroconverting spouse. Our study suggests that rates of HIV-1 seroconversion of sero-discordant partners are much higher within marriage than in the general population in Tanzania.
The major risk factor for HIV-1 seroconversion is sex of the serodiscordant spouse, with female spouses being at very high risk of acquiring HIV infection. This suggests that future programs that target serodiscordant couples could be a novel and effective means of preventing HIV-1 transmission in Tanzania.
Of these, 55, happened in Tanzania, where the prevalence of HIV is twice as high in women as in men [ 1 ].
Heterosexual transmission is the main driver of the HIV epidemic in Tanzania [ 2 ], with typical risk factors including presence of sexually transmitted infections STI , Schistosoma spp.