I have never really heard of it until now but have high Bilirubin levels with no other signs of liver disease. I have felt fatigue for the last couple of years now and notice things get worst if I work out at the gym or over do sports in general. A lot of days I feel a kind of brain fog and also have some joint pain especially in my knees and ankles. Hi J, if you've not already seen it then the British Liver Trust has a page dedicated to Gilbert's Syndrome at:- britishlivertrust.
No doubt some of our other members with GS will be along at some point to share their experience and offer support.
Any ideas on how you go about being diagnosed initially? Should my GP send me for further blood tests? In most cases doctors should be able to establish diagnosis on the basis of liver blood tests and jaundice, if you have it. Sometimes β but rarely β a blood test is taken before and after a 48 hour diet in which you are required to reduce your calorie intake.
In people with GS a significant increase in their bilirubin levels is usually seen to follow this. Liver blood tests are used to indicate whether your liver is inflamed hepatitis , damaged or not working properly.
They measure levels of certain enzyme and protein substances in your blood that may alter when liver damage is present. Raised and heavily unconjugated bilirubin in your blood is abnormal. When this is the only abnormal result, it is seen as a strong indication that you may have GS. Bilirubin levels can, however, fluctuate in GS and it is possible that they can be within the normal range over a period of time.
