Official websites use. Share sensitive information only on official, secure websites. E-mail: chaigneau. Solitary fibrous tumor is a rare tumor type and has an unpredictable course. It is characterized by a typical architecture and immuno-histochemistry tests. The most important prognostic factor is the complete resection of primary tumor. Treatment of recurrences is not clearly established. If a solitary fibrous tumor is too advanced to allow surgical resection, radiotherapy and chemotherapy may be used.
We report the case of man with metastatic solitary fibrous tumor treated with trabectedin, administered at a dose of 1. After 3 cycles, metastases had significantly decreased. Recurrence of the disease was demonstrated 8 months after the start of trabectedin. This case shows that trabectedin is a possible treatment option. Treatment of recurrences is poorly codified. The surgery remains probably the reference. In the forms too advanced for a surgical solution, it is usual to use radiotherapy and chemotherapy.
We describe a case report of a year-old man with metastatic solitary fibrous tumor treated with trabectedin. On July , a year old man without any relevant medical history had an assessment for chronic cough. Chest radiography revealed a left retro-cardiac thoracic mass. CT-scan found a voluminous solid, heterogeneous, well-encapsulated mass, with benign aspect, developed on lower half of left thorax. Lung biopsy concluded on solitary fibrous tumor SFT of the pleura.
Surgical resection was performed on October Histological examination confirmed the diagnosis of STF and surgical margins appeared free. In spite that this subtype of mesenchymatous tumor is widely considered as benign, most cases have the potential for local recurrence even after wide surgical excision.
Typically, patient received regular follow-up examination including thoracic CT-scan. In February , CT-scan revealed a unique 8 mm-lesion in the left lung and three other lesions on the right lung. Physical exam had not revealed any significant abnormalities associated with a good performance status. No complaints or functional limitations were described. These micronodules were totally nonspecific and asymptomatic.
