Noninvasive mechanical ventilation is sufficiently widely used to motivate bench studies for evaluating and comparing performances of the domiciliary ventilators. In most if not in all of the previous studies, ventilators were tested in a single or a very few conditions, chosen to avoid asynchrony events. Such a practice does not reflect how the ventilator is able to answer the demand from a large cohort of patients with their inherent inter-patient variability.
Three lung mechanics obstructive, restrictive and normal were simulated using a mechanical lung ASL driven by a realistic muscular pressure. For each of the nine ventilators tested, five different parameter settings were investigated. The results are synthesized in colored maps where each color represents the ventilator in ability to synchronize with a given muscular pressure dynamics. The lung model, the breathing frequency and the mouth occlusion pressure strongly affect the synchronizability of ventilators.
Triggering and pressurization performances of the nine ventilators present heterogeneities due to their different settings and operating strategies. Performances of domiciliary ventilators strongly depend not only on the breathing dynamics but also on the ventilator strategy. One given ventilator may be more adequate than another one for a given patient. Open Access.
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