Official websites use. Share sensitive information only on official, secure websites. For commercial re-use, please contact journals. Coronavirus disease COVID -associated acute kidney injury AKI frequency, severity and characterization in critically ill patients has not been reported. Single-centre cohort performed from 3 March to 14 April in four intensive care units in Bordeaux University Hospital, France.
A systematic urinary analysis was performed. The incidence, severity, clinical presentation, biological characterization transient versus persistent AKI; proteinuria, haematuria and glycosuria and short-term outcomes were evaluated.
Median [interquartile range IQR ] follow-up was 17 12β23 days. Keywords: acute interstitial nephritis, acute kidney injury, acute tubular injury, COVID, critically ill patients, renal replacement therapy. Since December , coronavirus disease COVID has infected nearly 5 million people worldwide, leading to more than deaths.
Globally, it has resulted in the confinement of nearly 3 billion people [ 1 , 2 ]. The severe respiratory damages requiring prolonged intubation have already been described, which are the determinant of intensive care unit ICU admission and have resulted in a consecutive risk of ICU saturation [ 3β6 ]. However, very few data are available in patients admitted to ICUs, where this incidence should be significantly higher.
The reason for this is not clearly established. AKI severity and potential recovery have not been reported. The need for renal replacement therapy RRT may considerably prolong the length of ICU hospitalization, leading to significant organizational and economic challenges for health-care systems. In addition, a high frequency of AKI could result in a very significant increase in the number of patients suffering from long-term chronic kidney disease CKD [ 7 ].
